Discrimination of oral squamous cell carcinoma from oral lichen planus by salivary metabolomics

Objective This study was conducted to distinguish salivary metabolites in oral squamous cell carcinoma (OSCC) from those in oral lichen planus (OLP) to identify practical biomarkers for the discrimination of OSCC from OLP. Subjects and Methods Whole unstimulated saliva samples were collected from patients with OSCC ( n = 34) and OLP ( n = 26). Hydrophilic metabolites in the saliva samples were comprehensively analysed by capillary...