SOX9/miR-203a axis drives PI3K/AKT signaling to promote esophageal cancer progression

Volume: 468, Pages: 14 - 26
Published: Jan 1, 2020
Abstract
Deregulation of SOX9 in esophageal cancer has been reported. However, the regulatory mechanisms underlying SOX9 during esophageal squamous cell carcinoma (ESCC) progression remain poorly understood. Here, we independently confirmed the increased SOX9 expression in two ESCC cohorts and its correlation with poor prognosis. We demonstrated that SOX9 was required for maintaining self-renewal, motility, and chemoresistance in vitro and that ectopic...
Paper Details
Title
SOX9/miR-203a axis drives PI3K/AKT signaling to promote esophageal cancer progression
Published Date
Jan 1, 2020
Volume
468
Pages
14 - 26
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