Mortalin restricts porcine epidemic diarrhea virus entry by downregulating clathrin-mediated endocytosis

Volume: 239, Pages: 108455 - 108455
Published: Dec 1, 2019
Abstract
Clathrin-mediated endocytosis is a mechanism used for the invasion of cells by a variety of viruses. Mortalin protein is involved in a variety of cellular functions and plays a role in viral infection. In this study, we found that mortalin significantly inhibited the replication of porcine epidemic diarrhea virus (PEDV) through restricting virus entry. Mechanistically, a biochemical interaction between the carboxyl terminus of mortalin and...
Paper Details
Title
Mortalin restricts porcine epidemic diarrhea virus entry by downregulating clathrin-mediated endocytosis
Published Date
Dec 1, 2019
Volume
239
Pages
108455 - 108455
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