Local ancestry at APOE modifies Alzheimer's disease risk in Caribbean Hispanics
Abstract
Introduction Although the relationship between APOE and Alzheimer's disease (AD) is well established in populations of European descent, the effects of APOE and ancestry on AD risk in diverse populations is not well understood. Methods Logistic mixed model regression and survival analyses were performed in a sample of 3067 Caribbean Hispanics and 3028 individuals of European descent to assess the effects of APOE genotype, local ancestry, and...
Paper Details
Title
Local ancestry at APOE modifies Alzheimer's disease risk in Caribbean Hispanics
Published Date
Oct 9, 2019
Journal
Volume
15
Issue
12
Pages
1524 - 1532
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