Donor cell engineering with GSK3 inhibitor–loaded nanoparticles enhances engraftment after in utero transplantation
Abstract
Intrauterine transplantation induces tolerance in the setting of the immature immue system but is hampered by low levels of engraftment. Glycogen synthase kinase 3 (GSK3) inhibition enhances stem cell proliferation, and Loukogeorgakis and colleagues report excellent engraftment in utero in mice following surface attachment of nanoparticles loaded with GSK3 inhibitor to donor stem...
Paper Details
Title
Donor cell engineering with GSK3 inhibitor–loaded nanoparticles enhances engraftment after in utero transplantation
Published Date
Nov 28, 2019
Journal
Volume
134
Issue
22
Pages
1983 - 1995
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Notes
History