The progress and development of GLUT1 inhibitors targeting cancer energy metabolism

Volume: 11, Issue: 17, Pages: 2333 - 2352
Published: Sep 1, 2019
Abstract
A major difference between glucose metabolism in cancer cells and normal cells is that glucose in cancer cells is preferably converted to lactate in aerobic conditions rather than oxidized in mitochondria. This process is called aerobic glycolysis, known as the 'Warburg effect'. In this review, we focus on the energy-metabolism characteristics between tumor and normal cells, analyzing the regulation mechanism of energy metabolism based on...
Paper Details
Title
The progress and development of GLUT1 inhibitors targeting cancer energy metabolism
Published Date
Sep 1, 2019
Volume
11
Issue
17
Pages
2333 - 2352
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