A systematic review and meta-analysis: Memantine augmentation in moderate to severe obsessive-compulsive disorder
Abstract
A considerable proportion of obsessive-compulsive disorder (OCD) patients receiving first-line pharmacological therapy, fail to fully respond to treatment and continue to exhibit significant symptoms. In this systematic review, we evaluate the efficacy of memantine, as a glutamate-modulating agent, in moderate to severe OCD. Single and double blinded as well as open-label trials of memantine augmentation in adults with OCD were considered....
Paper Details
Title
A systematic review and meta-analysis: Memantine augmentation in moderate to severe obsessive-compulsive disorder
Published Date
Dec 1, 2019
Volume
282
Pages
112602 - 112602
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