Reduced antibody levels and high seronegativity rates against vaccine preventable diseases pose a risk factor for infections in patients with solid and hematologic cancers

Background null New therapeutic concepts have led to substantial improvement in the survival of cancer patients. Yet, due to their compromised immune system these patients are at increased risk to encounter infections and need particular care with regard to vaccine preventable diseases (VPDs). Decreased seroprevalence to VPDs has already been reported in children suffering from malignancies, yet data from adult cancer patients are scarce. Here,...