EEG Scoring in Degenerative Brain Diseases of Childhood: The Pediatric Neurodegeneration EEG Scoring (PNES)

An increasing number of pediatric degenerative brain diseases is approaching curative therapy by new drugs and procedures (e.g. stem cell transplantation, gene therapy). In recent years, the natural course of clinical and neuroimaging findings in some of the neurodegenerative diseases has been described, offering the opportunity to quantify or estimate the efficacy of the treatment. To define the course of EEG changes as an additional and...