Review paper

Current state and future prospect of the therapeutic strategy targeting cysteinyl leukotriene metabolism in asthma

Volume: 57, Issue: 6, Pages: 534 - 543
Published: Nov 1, 2019
Abstract
Asthma is an allergic disorder with dominant type 2 airway inflammation, and its prevalence is increasing worldwide. Inhalation of corticosteroids is the primary treatment for asthma along with add-on drugs, including long-acting β2 agonists and/or cysteinyl leukotriene (cys-LT) receptor antagonists, in patients with poorly controlled asthma. Cys-LTs are composed of leukotriene C4 (LTC4), LTD4, and LTE4, which are enzymatically metabolized from...
Paper Details
Title
Current state and future prospect of the therapeutic strategy targeting cysteinyl leukotriene metabolism in asthma
Published Date
Nov 1, 2019
Volume
57
Issue
6
Pages
534 - 543
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