An Unusual Case of Lysosomal Paraprotein Accumulation in Glomerular Endothelial Cells
Abstract
Plasma cell dyscrasias (PCDs) are characterized by the excessive production of abnormal Igs, mainly free light chains (LCs) with nephrotoxic properties. Patients with PCDs develop a variety of renal diseases such as cast nephropathy (CN), amyloidosis, LC deposition disease (LCDD), and LC proximal tubulopathy. Cast nephopathy is characterized by intratubular cast formation of monoclonal LCs leading to renal dysfunction. LCDD and amyloidosis...
Paper Details
Title
An Unusual Case of Lysosomal Paraprotein Accumulation in Glomerular Endothelial Cells
Published Date
Jan 1, 2020
Journal
Volume
5
Issue
1
Pages
109 - 115
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History