MAST1-Gene Variations: A New Monogenetic Neuronal Migration Disorder Causing Congenital Bilateral Perisylvian Syndrome (CBPS)

Background: Congenital bilateral perisylvian syndrome (CBPS) is a rare cortical migration disorder associated with typical clinical and imaging features such as bilateral symmetrical polymicrogyria, either exclusively or mainly affecting the perisylvian region of the brain. Clinical features of CBPS often include oromotor dysfunction, epilepsy and variable degrees of developmental delay. There are multiple non-genetic causes of polymicrogyria...