Prognostic role of CD73 in metastatic non small cell lung cancer according to the presence of driver alterations

Background null CD73 is an enzyme involved in the conversion of extracellular AMP into adenosine. Adenosine inhibits T lymphocytes, contributing to immune escape. CD73 promotes proliferation and migration and has been associated to a negative prognosis in various cancers. Data are limited on its role in metastatic NSCLC, particularly with genetic drivers. null null null Methods null We collected patients (pts) with EGFR Mutant (EM), ALK...