Phylogeographic and phylodynamic approaches to epidemiological hypothesis testing

Abstract
Computational analyses of pathogen genomes are increasingly used to unravel the dispersal history and transmission dynamics of epidemics. Here, we show how to go beyond historical reconstructions and use spatially-explicit phylogeographic and phylodynamic approaches to formally test epidemiological hypotheses. We illustrate our approach by focusing on the West Nile virus (WNV) spread in North America that has been responsible for substantial...
Paper Details
Title
Phylogeographic and phylodynamic approaches to epidemiological hypothesis testing
Published Date
Oct 1, 2019
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