[Research progress of CRISPR-Cas9 system for gene therapy].
Abstract
The clustered regulatory interspaced short palindromic repeat-Cas9 (CRISPR-Cas9) system is the part of the prokaryotic immune system, which could recognize and delete the exogenous sequences originated from virus or plasmid. Based on its mechanism, CRISPR-Cas9 system was developed into the new generation of gene editing tool. Compared to the existed technologies such as ES targeting, ZFN or TALEN, CRISPR-Cas9 system is a more efficient,...
Paper Details
Title
[Research progress of CRISPR-Cas9 system for gene therapy].
Published Date
Jul 25, 2016
Journal
Volume
32
Issue
7
Pages
861 - 869
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