Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging
Abstract
We have developed a human bronchial epithelial (HBE) cell and endothelial cell co-cultured microfluidic model to mimic the in vivo human airway. This airway-on-a-chip was designed with a central epithelial channel and two flanking endothelial channels, with a three-dimensional monolayers of cells growing along the four walls of the channel, forming central clear lumens. These cultures mimic airways and microvasculature in vivo. The central...
Paper Details
Title
Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging
Published Date
Sep 30, 2019
Journal
Volume
10
Issue
10
Pages
5414 - 5414
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