A genetic risk score predicts coronary artery disease in familial hypercholesterolaemia: enhancing the precision of risk assessment
Abstract
Familial hypercholesterolaemia (FH) is associated with increased risk of coronary artery disease (CAD); however, risk prediction and stratification remain a challenge. Genetic risk scores (GRS) may have utility in identifying FH patients at high CAD risk. The study included 811 patients attending the lipid disorders clinic at Royal Perth Hospital with mutation-positive (n = 251) and mutation-negative (n = 560) FH. Patients were genotyped for a...
Paper Details
Title
A genetic risk score predicts coronary artery disease in familial hypercholesterolaemia: enhancing the precision of risk assessment
Published Date
Oct 9, 2019
Journal
Volume
97
Issue
2
Pages
257 - 263
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