Casein kinase 1 family proteins promote Slimb-dependent Expanded degradation
Abstract
Hippo signalling integrates diverse stimuli related to epithelial architecture to regulate tissue growth and cell fate decisions. The Hippo kinase cascade represses the growth-promoting transcription co-activator Yorkie. The FERM protein Expanded is one of the main upstream Hippo signalling regulators in Drosophila as it promotes Hippo kinase signalling and directly inhibits Yorkie. To fulfil its function, Expanded is recruited to the plasma...
Paper Details
Title
Casein kinase 1 family proteins promote Slimb-dependent Expanded degradation
Published Date
Sep 30, 2019
Journal
Volume
8
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Notes
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