New Way Forward for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Tumors with an LC-MS/MS Panel of Indole Biomarkers

Diagnosis and surveillance of gastroenteropancreatic neuroendocrine tumors (GEP-NETs)2 involve a repertoire of several different biochemical tests with some differences in utility according to classifications and guidelines from the North American Neuroendocrine Tumor Society (1) and the European Neuroendocrine Tumor Society (2). Measured biomarkers include plasma chromogranin A, urinary or plasma 5-hydroxyindole acetic acid, platelet or whole...