Molecular Alterations in Thyroid Carcinoma

Volume: 12, Issue: 4, Pages: 921 - 930
Published: Dec 1, 2019
Abstract
Thyroid carcinoma is the most common cancer in the endocrine system. Recent advances, using next-generation sequencing, have shed light on the molecular pathogenesis of thyroid cancer. Constitutional activation of the mitogen-activated protein kinase pathway through RAS mutation, BRAF mutation, and/or fusions involving receptor tyrosine kinase (eg, (REarranged during Transfection) RET-PTC) plays a central role in tumorigenesis and opens doors to...
Paper Details
Title
Molecular Alterations in Thyroid Carcinoma
Published Date
Dec 1, 2019
Volume
12
Issue
4
Pages
921 - 930
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