HIGD2A is required for assembly of the COX3 module of human mitochondrial complex IV
Abstract
Assembly factors play a critical role in the biogenesis of mitochondrial respiratory chain complexes I-IV where they assist in the membrane insertion of subunits, attachment of co-factors, and stabilization of assembly intermediates. The major fraction of complexes I, III and IV are present together in large molecular structures known as respiratory chain supercomplexes. A number of assembly factors have been proposed as required for...
Paper Details
Title
HIGD2A is required for assembly of the COX3 module of human mitochondrial complex IV
Published Date
Dec 19, 2019
Journal
Pages
787721
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