Unusual Drug Test Results for a Patient on Buprenorphine and Naloxone

A 28-year-old man with a history of opioid abuse, currently prescribed Suboxone® to manage his opioid use disorder, submitted a urine specimen for a drug screen to verify abstinence from illicit compounds and compliance with the prescribed medication. The specimen screened positive by immunoassay (IA) for oxycodone and buprenorphine. Based on these results, the physician requested confirmation testing by LC-MS/MS and requested help interpreting...