Analysis of the B cell receptor repertoire in six immune-mediated diseases
Abstract
B cells are important in the pathogenesis of many, and perhaps all, immune-mediated diseases. Each B cell expresses a single B cell receptor (BCR)1, and the diverse range of BCRs expressed by the total B cell population of an individual is termed the 'BCR repertoire'. Our understanding of the BCR repertoire in the context of immune-mediated diseases is incomplete, and defining this could provide new insights into pathogenesis and therapy. Here,...
Paper Details
Title
Analysis of the B cell receptor repertoire in six immune-mediated diseases
Published Date
Sep 25, 2019
Journal
Volume
574
Issue
7776
Pages
122 - 126
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