Experimental characterization and molecular dynamic simulation of ketoprofen-cyclodextrin complexes

Traditional experimental methods have their own limitations to obtain a deep understanding about the molecular mechanism of drug-cyclodextrin (CD) complexes. Thus, present research investigated the molecular interactions between poorly water-soluble drug Ketoprofen (KTP) and six commonly used CDs by combined experimental and modeling methods. Experimental characterizations of prepared KTP-CD complexes observed the crystalline changes and...