APPLES: Scalable Distance-Based Phylogenetic Placement with or without Alignments
Abstract
Placing a new species on an existing phylogeny has increasing relevance to several applications. Placement can be used to update phylogenies in a scalable fashion and can help identify unknown query samples using (meta-)barcoding, skimming, or metagenomic data. Maximum likelihood (ML) methods of phylogenetic placement exist, but these methods are not scalable to reference trees with many thousands of leaves, limiting their ability to enjoy...
Paper Details
Title
APPLES: Scalable Distance-Based Phylogenetic Placement with or without Alignments
Published Date
Sep 23, 2019
Journal
Volume
69
Issue
3
Pages
566 - 578
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