Further in vivo characterization of [ ¹¹ C]‐(+)‐PHNO uptake into a retina‐like region of interest in humans

The neurotransmitter dopamine is present in the retina and is involved in several modulatory functions. Unlike in rodents, dopamine D 3 receptors are expressed in the retina of humans. Recently, uptake of the D 3 receptor‐preferring radiotracer [ 11 C]‐(+)‐PHNO has been observed in a retina‐like region of interest (ROI) in humans. Here, we attempted to quantify [ 11 C]‐(+)‐PHNO uptake into this ROI using an independent sample, employing an...