Comparison of BEAMing and Droplet Digital PCR for Circulating Tumor DNA Analysis
Abstract
BACKGROUND Circulating tumor DNA (ctDNA) assays are increasingly used for clinical decision-making, but it is unknown how well different assays agree. We aimed to assess the agreement in ctDNA mutation calling between BEAMing (beads, emulsion, amplification, and magnetics) and droplet digital PCR (ddPCR), 2 of the most commonly used digital PCR techniques for detecting mutations in ctDNA. METHODS Baseline plasma samples from patients with...
Paper Details
Title
Comparison of BEAMing and Droplet Digital PCR for Circulating Tumor DNA Analysis
Published Date
Nov 1, 2019
Journal
Volume
65
Issue
11
Pages
1405 - 1413
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