Asthma pharmacotherapy: an update on leukotriene treatments

Introduction: Asthma is a chronic inflammatory disease of the airways with a large heterogeneity of clinical phenotypes. There has been increasing interest regarding the role of cysteinyl leukotriene (LT) and leukotriene receptor antagonists (LTRA) in asthma treatment.Areas covered: This review summarized the data (published in PubMed during 1984–2019) regarding LTRA treatment in asthma and LTs-related airway inflammation mechanisms. Involvement...