Dynamin and reverse-mode sodium calcium exchanger blockade confers neuroprotection from diffuse axonal injury
Abstract
Mild traumatic brain injury (mTBI) is a frequently overlooked public health concern that is difficult to diagnose and treat. Diffuse axonal injury (DAI) is a common mTBI neuropathology in which axonal shearing and stretching induces breakdown of the cytoskeleton, impaired axonal trafficking, axonal degeneration, and cognitive dysfunction. DAI is becoming recognized as a principal neuropathology of mTBI with supporting evidence from animal model,...
Paper Details
Title
Dynamin and reverse-mode sodium calcium exchanger blockade confers neuroprotection from diffuse axonal injury
Published Date
Sep 27, 2019
Journal
Volume
10
Issue
10
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