S36COMBINATORIAL PHARMACOGENOMIC TESTING IMPROVES OUTCOMES FOR PATIENTS TAKING MEDICATIONS WITH GENE-DRUG INTERACTIONS IN A RANDOMIZED, CONTROLLED TRIAL

This study assessed the efficacy and safety of the anti-CD40 monoclonal antibody bleselumab (ASKP1240) in de novo kidney transplant recipients over 36 months posttransplant. Transplant recipients were randomized (1:1:1) to standard of care (SoC: 0.1 mg/kg per day immediate-release tacrolimus [IR-TAC]; target minimum blood concentration [Ctrough] 4-11 ng/mL plus 1 g mycophenolate mofetil [MMF] twice daily) or bleselumab (200 mg on days...