CAPS1 Suppresses Tumorigenesis in Cholangiocarcinoma

CAPS1 (calcium-dependent activator protein for secretion) is a multi-domain protein involved in regulating exocytosis of synaptic vesicles and dense-core vesicles. However, the expression and function of CAPS1 in cholangiocarcinoma (CCA) remains unclear. In the present study, we explored the role of CAPS1 in CCA carcinogenesis. CAPS1 expression was explored using western blotting and immunohistochemistry in four CCA cell lines and clinical...