Real-time monitoring apoptosis and autophagy among multiple organelles by adjusting the slight structure

Conventional probes are often difficult to observe apoptosis and autophagy at the same time. Herein, a series of small molecule multifunctional probes (L1-L6) were developed conveniently. Among, probes L1-L2 located in the mitochondria and L3 located in the lysosome in live cells, probes L4-L5 targeting mitochondria and L6 targeting lysosomes in living cells were further developed as a comparison. The experiment results of cells apoptosis showed...