Comparative analysis of fusion tags used to functionalize recombinant antibodies
Abstract
Recombinant antibodies can be expressed as fusion constructs in combination with tags which simplify their engineering into reliable and homogeneous immunoreagents by allowing site-specific, 1:1 functionalization. Several tags and corresponding reagents for recombinant protein derivatization have been proposed but benchmarking surveys for the evaluation of their effect on the characteristics of recombinant antibodies have not been reported. In...
Paper Details
Title
Comparative analysis of fusion tags used to functionalize recombinant antibodies
Published Date
Feb 1, 2020
Volume
166
Pages
105505 - 105505
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