HO-1 mitigates acute kidney injury and subsequent kidney-lung cross-talk
Abstract
Ischemia-reperfusion injury (IRI) is a leading cause of acute kidney injury (AKI), which contributes to the development of chronic kidney disease (CKD). IRI-induced AKI releases proinflammatory cytokines (e.g. IL-1β, TNF-α, IL-6) that induce a systemic inflammatory response, resulting in proinflammatory cells recruitment and remote organ damage. AKI is associated with poor outcomes, particularly when extrarenal complications or distant organ...
Paper Details
Title
HO-1 mitigates acute kidney injury and subsequent kidney-lung cross-talk
Published Date
Sep 29, 2019
Journal
Volume
53
Issue
9-10
Pages
1035 - 1043
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Notes
History