ILC2s and Basophils Team Up to Orchestrate IL-33–Induced Atopic Dermatitis

Volume: 139, Issue: 10, Pages: 2077 - 2079
Published: Oct 1, 2019
Abstract
In this issue, Imai et al. (2019) provide new insights into the pathophysiology of AD-like inflammation using their model (Imai et al., 2013) and ask how ILC2s and basophils contribute to the IL-33–induced AD-like inflammation. Their findings show that continuous expression of IL-33 in keratinocytes is sufficient to cause AD-like inflammation in mice, and that this occurrence is largely independent of adaptive immune cells and is mediated by...
Paper Details
Title
ILC2s and Basophils Team Up to Orchestrate IL-33–Induced Atopic Dermatitis
Published Date
Oct 1, 2019
Volume
139
Issue
10
Pages
2077 - 2079
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