Pharmacological inhibition of Notch signaling regresses pre-established abdominal aortic aneurysm
Abstract
Abdominal aortic aneurysm (AAA) is characterized by transmural infiltration of myeloid cells at the vascular injury site. Previously, we reported preventive effects of Notch deficiency on the development of AAA by reduction of infiltrating myeloid cells. In this study, we examined if Notch inhibition attenuates the progression of pre-established AAA and potential implications. Pharmacological Notch inhibitor...
Paper Details
Title
Pharmacological inhibition of Notch signaling regresses pre-established abdominal aortic aneurysm
Published Date
Sep 17, 2019
Journal
Volume
9
Issue
1
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