Compartment-restricted and rate-controlled dual drug delivery system using a biosilica-enveloped ferritin cage

Combinational therapy has been exploited to enhance therapeutic efficiency against cancer by overcoming drug resistance and side-effects or by synergistic effects of multi drugs. However, the conventional co-delivery of combination regimens is often limited by the differences in physicochemical properties among different drugs. Here, to solve this problem, we demonstrated an advanced dual drug delivery system (dDDS) using a R5 peptide-fused...