Pilot GWAS of caries in African-Americans shows genetic heterogeneity

Dental caries is the most common chronic disease in the US and disproportionately affects racial/ethnic minorities. Caries is heritable, and though genetic heterogeneity exists between ancestries for a substantial portion of loci associated with complex disease, a genome-wide association study (GWAS) of caries specifically in African Americans has not been performed previously.We performed exploratory GWAS of dental caries in 109 African...