The relationship of airway structural changes to blood and bronchoalveolar lavage biomarkers, and lung function abnormalities in asthma

Background Airway structural changes are important in asthma pathology and require further investigations. Objective We sought to evaluate which computed tomography (CT) indices, bronchial histological traits, or blood and bronchoalveolar lavage (BAL) biomarkers correlate best with lung function abnormalities in asthma. Methods In 105 white adult asthmatics (53 with a component of fixed airflow obstruction), we determined airway cross‐sectional...