Drug development research for novel adiponectin receptor-targeted antidiabetic drugs contributing to healthy longevity
Abstract
It is well recognized that the decrease of adiponectin associated with high-fat diet and lack of exercise accounts for the onset of insulin resistance, type 2 diabetes, the metabolic syndrome, and cardiovascular disease. Our research efforts have led to the identification of adiponectin receptors, AdipoR1 and AdipoR2, with the former shown to activate AMP kinase in the liver and the latter shown to activate peroxisome proliferator-activated...
Paper Details
Title
Drug development research for novel adiponectin receptor-targeted antidiabetic drugs contributing to healthy longevity
Published Date
Sep 19, 2019
Journal
Volume
10
Issue
4
Pages
237 - 244
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