Mitochondrial dysfunction is associated with long-term cognitive impairment in an animal sepsis model
Abstract
Background: Several different mechanisms have been proposed to explain long-term cognitive impairment in sepsis survivors. The role of persisting mitochondrial dysfunction is not known. We thus sought to determine whether stimulation of mitochondrial dynamics improves mitochondrial function and long-term cognitive impairment in an experimental model of sepsis.Methods: Sepsis was induced in adult Wistar rats by cecal ligation and perforation...
Paper Details
Title
Mitochondrial dysfunction is associated with long-term cognitive impairment in an animal sepsis model
Published Date
Sep 1, 2019
Journal
Volume
133
Issue
18
Pages
1993 - 2004
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History