RAGE is a Potential Cause of Onset and Progression of Nonalcoholic Fatty Liver Disease

Fatty liver is a rising global health concern, significantly increasing the burden of health care cost. Nonalcoholic fatty liver disease (NAFLD) has a correlation with metabolic syndrome and its complications.We reviewed the literature regarding the mechanisms of developing NAFLD through AGE-RAGE signaling.NAFLD, metabolic syndrome, and production of advanced glycation end-products (AGEs) share many common risk factors and appear to be...