Review paper
An overview and metanalysis of machine and deep learning-based CRISPR gRNA design tools
Abstract
The CRISPR-Cas9 system has become the most promising and versatile tool for genetic manipulation applications. Albeit the technology has been broadly adopted by both academic and pharmaceutic societies, the activity (on-target) and specificity (off-target) of CRISPR-Cas9 are decisive factors for any application of the technology. Several in silico gRNA activity and specificity predicting models and web tools have been developed, making it much...
Paper Details
Title
An overview and metanalysis of machine and deep learning-based CRISPR gRNA design tools
Published Date
Sep 27, 2019
Journal
Volume
17
Issue
1
Pages
13 - 22
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