Gene expression profiling of single cells from archival tissue with laser-capture microdissection and Smart-3SEQ
Abstract
RNA sequencing (RNA-seq) is a sensitive and accurate method for quantifying gene expression. Small samples or those whose RNA is degraded, such as formalin-fixed paraffin-embedded (FFPE) tissue, remain challenging to study with nonspecialized RNA-seq protocols. Here, we present a new method, Smart-3SEQ, that accurately quantifies transcript abundance even with small amounts of total RNA and effectively characterizes small samples extracted by...
Paper Details
Title
Gene expression profiling of single cells from archival tissue with laser-capture microdissection and Smart-3SEQ
Published Date
Sep 13, 2019
Journal
Volume
29
Issue
11
Pages
1816 - 1825
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History