From Individual to Population Preferences: Comparison of Discrete Choice and Dirichlet Models for Treatment Benefit-Risk Tradeoffs

Introduction. The Dirichlet distribution has been proposed for representing preference heterogeneity, but there is limited evidence on its suitability for modeling population preferences on treatment benefits and risks. Methods. We conducted a simulation study to compare how the Dirichlet and standard discrete choice models (multinomial logit [MNL] and mixed logit [MXL]) differ in their convergence to stable estimates of population benefit-risk...