Protective microbiomes can limit the evolution of host pathogen defense.

Volume: 3, Issue: 5, Pages: 534 - 543
Published: Sep 11, 2019
Abstract
The evolution of host immunity occurs in the context of the microbiome, but little theory exists to predict how resistance against pathogens might be influenced by the need to tolerate and regulate commensal microbiota. We present a general model to explore the optimal investment in host immunity under conditions in which the host can, versus cannot easily distinguish among commensal versus pathogenic bacteria, and when commensal microbiota can,...
Paper Details
Title
Protective microbiomes can limit the evolution of host pathogen defense.
Published Date
Sep 11, 2019
Volume
3
Issue
5
Pages
534 - 543
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