Alvimopan for the Prevention of Postoperative Ileus in Inflammatory Bowel Disease Patients

Postoperative ileus (POI) is a temporary delay of coordinated intestinal peristalsis. Alvimopan, an oral peripherally acting mu-opioid receptor antagonist approved for accelerating gastrointestinal recovery, has never been studied specifically in patients with inflammatory bowel disease (IBD). To investigate the efficacy of alvimopan in preventing POI among IBD patients. A retrospective chart review was conducted on 246 IBD patients undergoing...