Patiromer versus placebo to enable spironolactone use in patients with resistant hypertension and chronic kidney disease (AMBER): a phase 2, randomised, double-blind, placebo-controlled trial.

Volume: 394, Issue: 10208, Pages: 1540 - 1550
Published: Oct 26, 2019
Abstract
Summary null Background null Spironolactone is effective at reducing blood pressure in patients with uncontrolled resistant hypertension. However, the use of spironolactone in patients with chronic kidney disease can be restricted by hyperkalaemia. We evaluated use of the potassium binder patiromer to allow more persistent use of spironolactone in patients with chronic kidney disease and resistant hypertension. null Methods null In this phase 2...
Paper Details
Title
Patiromer versus placebo to enable spironolactone use in patients with resistant hypertension and chronic kidney disease (AMBER): a phase 2, randomised, double-blind, placebo-controlled trial.
Published Date
Oct 26, 2019
Journal
Volume
394
Issue
10208
Pages
1540 - 1550
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