Predicting Persistent Opioid Use, Abuse and Toxicity Among Cancer Survivors

While opioids play a critical role in the management of cancer pain, the ongoing opioid epidemic has raised concerns regarding their persistent use and abuse. An individualized assessment of benefits and risks is required for optimal management with opioids. Current guidelines for risk stratification, however, are based on expert opinion or instruments validated in non-oncology cohorts that omit numerous relevant factors for cancer patients. The...