p97 regulates GluA1 homomeric AMPA receptor formation and plasma membrane expression
Abstract
The α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptors (AMPARs) mediate the fast excitatory synaptic transmission in the mammalian brain and are important for synaptic plasticity. In particular, the rapid insertion of the GluA1 homomeric (GluA1-homo) AMPARs into the postsynaptic membrane is considered to be critical in the expression of hippocampal CA1 long-term potentiation (LTP), which is important for certain...
Paper Details
Title
p97 regulates GluA1 homomeric AMPA receptor formation and plasma membrane expression
Published Date
Sep 9, 2019
Journal
Volume
10
Issue
1
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